Detail for FLT3


Full Name

Fms Related Tyrosine Kinase 3

Gene Name

GC13M028003

NCBI ID

Related Disease

  • Acute myeloid leukaemia [ref.1]

Therapy Method

  • [ref.]

Function

HGF (Hepatocyte Growth Factor) is a Protein Coding gene. Diseases associated with HGF include Deafness, Autosomal Recessive 39 and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb. Among its related pathways are ERK Signaling and Focal Adhesion. Gene Ontology (GO) annotations related to this gene include identical protein binding and serine-type endopeptidase activity. An important paralog of this gene is MST1.

Related Pathway/CSCs feature

Reference

  • [1] Resistance to FLT3 inhibition in an in vitro model of primary AML cells with a stem cell phenotype in a defined microenvironment.
    Leukemia.2008 Jul;22(7):1395-401.. [ 18509353 ]

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