Detail for ABCG2


Full Name

ATP Binding Cassette Subfamily G Member 2 (Junior Blood Group)

Gene Name

GC04M088090

NCBI ID

Related Disease

  • Glioblastoma [ref.1]

Therapy Method

  • [ref.]

Function

HGF (Hepatocyte Growth Factor) is a Protein Coding gene. Diseases associated with HGF include Deafness, Autosomal Recessive 39 and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb. Among its related pathways are ERK Signaling and Focal Adhesion. Gene Ontology (GO) annotations related to this gene include identical protein binding and serine-type endopeptidase activity. An important paralog of this gene is MST1.

Related Pathway/CSCs feature

Reference

  • [1] The ABCG2 resistance network of glioblastoma.
    Cell Cycle. 2009 Sep 15;8(18):2936-44.. [ 19713741 ]

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