Detail for TNF-R1


Full Name

TNF receptor-1

Gene Name

GC12M006308

NCBI ID

Related Disease

  • Glioblastoma [ref.1]

Therapy Method

  • [ref.]

Function

HGF (Hepatocyte Growth Factor) is a Protein Coding gene. Diseases associated with HGF include Deafness, Autosomal Recessive 39 and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb. Among its related pathways are ERK Signaling and Focal Adhesion. Gene Ontology (GO) annotations related to this gene include identical protein binding and serine-type endopeptidase activity. An important paralog of this gene is MST1.

Related Pathway/CSCs feature

Reference

  • [1] Endothelial expression of TNF receptor-1 generates a proapoptotic signal inhibited by integrin α6β1 in glioblastoma.
    Cancer Res.2012 Mar 15;72(6):1428-37.. [ 22396498 ]

Back to top