Detail for CCL2


Full Name

Chemokine (C-C motif) ligand 2

Gene Name

GC17P034255

NCBI ID

Related Disease

  • Breast cancer [ref.1]

Therapy Method

  • [ref.]

Function

HGF (Hepatocyte Growth Factor) is a Protein Coding gene. Diseases associated with HGF include Deafness, Autosomal Recessive 39 and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb. Among its related pathways are ERK Signaling and Focal Adhesion. Gene Ontology (GO) annotations related to this gene include identical protein binding and serine-type endopeptidase activity. An important paralog of this gene is MST1.

Related Pathway/CSCs feature

Reference

  • [1] CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells.
    Cancer Res.2012 Jun 1;72(11):2768-79.. [ 22472119 ]

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