Detail for STAT3


Full Name

Signal Transducer And Activator Of Transcription 3

Gene Name

GC17M042313

NCBI ID

Related Disease

  • Osteosarcoma [ref.1]

Therapy Method

  • [ref.]

Function

HGF (Hepatocyte Growth Factor) is a Protein Coding gene. Diseases associated with HGF include Deafness, Autosomal Recessive 39 and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb. Among its related pathways are ERK Signaling and Focal Adhesion. Gene Ontology (GO) annotations related to this gene include identical protein binding and serine-type endopeptidase activity. An important paralog of this gene is MST1.

Related Pathway/CSCs feature

Reference

  • [1] STAT3 activation by IL-6 from mesenchymal stem cells promotes the proliferation and metastasis of osteosarcoma.
    Cancer Lett.2012 Dec 1;325(1):80-8.. [ 22743617 ]

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