Detail for KDM3


Full Name

Gene Name

Related Disease

  • Human colorectal cancer [ref.1]

Therapy Method

  • [ref.]

Function

HGF (Hepatocyte Growth Factor) is a Protein Coding gene. Diseases associated with HGF include Deafness, Autosomal Recessive 39 and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb. Among its related pathways are ERK Signaling and Focal Adhesion. Gene Ontology (GO) annotations related to this gene include identical protein binding and serine-type endopeptidase activity. An important paralog of this gene is MST1.

Related Pathway/CSCs feature

Reference

  • [1] KDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/β-catenin signalling.
    Nat Commun.. [ 28440295 ]

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