Detail for OPCs


Full Name

Oligomeric proanthocyanidins

Gene Name

Detect

NCBI ID

Related Disease

  • Colorectal cancer [ref.1]

Therapy Method

  • [ref.]

Function

HMGA2 (High Mobility Group AT-Hook 2) is a Protein Coding gene. Diseases associated with HMGA2 include Salivary Gland Adenoma, Pleomorphic and Silver-Russell Syndrome. Among its related pathways are MicroRNAs in cancer and DNA Damage/Telomere Stress Induced Senescence. Gene Ontology (GO) annotations related to this gene include enzyme binding and transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding.

Related Pathway/CSCs feature

Reference

  • [1] Oligomeric proanthocyanidins (OPCs) target cancer stem-like cells and suppress tumor organoid formation in colorectal cancer.
    Sci Rep.2018 Feb 20;8(1):3335.. [ 29463813 ]

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