Detail for KLF4

Full Name

Kruppel-like factor 4

Gene Name



Related Disease

  • Osteosarcoma [ref.1]

Therapy Method

  • [ref.]


KLF4 (Kruppel Like Factor 4) is a Protein Coding gene. Diseases associated with KLF4 include Secretory Meningioma and Venous Hemangioma. Among its related pathways are Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) and SRF and miRs in Smooth Muscle Differentiation and Proliferation. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and transcription factor binding. An important paralog of this gene is KLF2.

Related Pathway/CSCs feature


  • [] 1KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells.
    Acta Pharmacol Sin.2018 Jun 21.. [ 29930276 ]

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