Detail for FOXC1


Full Name

Forkhead box C1

Gene Name

GC06P001610

NCBI ID

Related Disease

  • NSCLC [ref.1]

Therapy Method

  • [ref.]

Function

FOXC1 (Forkhead Box C1) is a Protein Coding gene. Diseases associated with FOXC1 include Anterior Segment Dysgenesis 3 and Axenfeld-Rieger Syndrome, Type 3. Among its related pathways are Transcriptional Regulatory Network in Embryonic Stem Cell and Heart Development. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and transcription factor binding. An important paralog of this gene is FOXC2.

Related Pathway/CSCs feature

Reference

  • [1] FOXC1 induces cancer stem cell-like properties through upregulation of beta-catenin in NSCLC.
    J Exp Clin Cancer Res.2018 Sep 6;37(1):220.. [ 30189871 ]

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