Detail for LRP8


Full Name

LDL Receptor Related Protein 8

Gene Name

GC01M053243

NCBI ID

Related Disease

  • Breast cancer [ref.1]

Therapy Method

  • [ref.]

Function

LRP8 (LDL Receptor Related Protein 8) is a Protein Coding gene. Diseases associated with LRP8 include Myocardial Infarction and Osteoporosis-Pseudoglioma Syndrome. Among its related pathways are Reelin Pathway (Cajal-Retzius cells) and Metabolism. Gene Ontology (GO) annotations related to this gene include calcium ion binding and kinesin binding. An important paralog of this gene is LDLR.

Related Pathway/CSCs feature

Reference

  • [1] Targeting LRP8 inhibits breast cancer stem cells in triple-negative breast cancer.
    Cancer Lett.2018 Dec 1;438:165-173.. [ 30227220 ]

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