Detail for EZH2

Full Name

Enhancer of zeste homolog 2

Gene Name



Related Disease

  • PAN [ref.1]

Therapy Method

  • [ref.]


EZH2 (Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit) is a Protein Coding gene. Diseases associated with EZH2 include Weaver Syndrome and Cholangiolocellular Carcinoma. Among its related pathways are Cellular Senescence (REACTOME) and MicroRNAs in cancer. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and chromatin binding. An important paralog of this gene is EZH1.

Related Pathway/CSCs feature


  • [1] Role of EZH2 in cancer stem cells: from biological insight to a therapeutic target.
    Oncotarget.2017 Jun 6;8(23):37974-37990.. [ 28415635 ]

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