Detail for EZH2


Full Name

Enhancer of zeste homolog 2

Gene Name

GC07M148807

NCBI ID

Related Disease

  • PAN [ref.1]

Therapy Method

  • [ref.]

Function

EZH2 (Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit) is a Protein Coding gene. Diseases associated with EZH2 include Weaver Syndrome and Cholangiolocellular Carcinoma. Among its related pathways are Cellular Senescence (REACTOME) and MicroRNAs in cancer. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and chromatin binding. An important paralog of this gene is EZH1.

Related Pathway/CSCs feature

Reference

  • [1] Role of EZH2 in cancer stem cells: from biological insight to a therapeutic target.
    Oncotarget.2017 Jun 6;8(23):37974-37990.. [ 28415635 ]

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