Detail for BAG3


Full Name

BCL2 Associated Athanogene 3

Gene Name

GC10P119651

NCBI ID

Related Disease

  • Breast cancer [ref.1]

Therapy Method

  • [ref.]

Function

BAG3 (BCL2 Associated Athanogene 3) is a Protein Coding gene. Diseases associated with BAG3 include Myopathy, Myofibrillar, 6 and Cardiomyopathy, Dilated, 1Hh. Among its related pathways are Apoptosis Modulation and Signaling and Busulfan Pathway, Pharmacodynamics. Gene Ontology (GO) annotations related to this gene include chaperone binding. An important paralog of this gene is BAG4.

Related Pathway/CSCs feature

Reference

  • [1] BAG3 promotes stem cell-like phenotype in breast cancer by upregulation of CXCR4 via interaction with its transcript.
    Cell Death Dis.2017 Jul 13;8(7):e2933.. [ 28703799 ]

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