Detail for ZEB1


Full Name

Zinc finger E-box binding homeobox 1 protein

Gene Name

GC10P031330

NCBI ID

Related Disease

  • Breast cancer [ref.1]

Therapy Method

  • [ref.]

Function

ZEB1 (Zinc Finger E-Box Binding Homeobox 1) is a Protein Coding gene. Diseases associated with ZEB1 include Corneal Dystrophy, Fuchs Endothelial, 6 and Corneal Dystrophy, Posterior Polymorphous, 3. Among its related pathways are ERK Signaling and MicroRNAs in cancer. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and chromatin binding. An important paralog of this gene is ZEB2.

Related Pathway/CSCs feature

Reference

  • [1] ZEB1 confers stem cell-like properties in breast cancer by targeting neurogenin-3.
    Oncotarget.2017 Apr 13;8(33):54388-54401.. [ 28903350 ]

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