Detail for PUMA


Full Name

p53-upregulated modulator of apoptosis

Gene Name

GC19M047220

NCBI ID

Related Disease

  • Breast cancer [ref.1]

Therapy Method

  • [ref.]

Function

BBC3 (BCL2 Binding Component 3) is a Protein Coding gene. Among its related pathways are Gene Expression and Apoptosis and survival_Regulation of Apoptosis by Mitochondrial Proteins.

Related Pathway/CSCs feature

Reference

  • [1] Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis.
    J Clin Invest.2018 Jan 2;128(1):531-544.. [ 29227280 ]

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