PDK1 (Pyruvate Dehydrogenase Kinase 1) is a Protein Coding gene. Diseases associated with PDK1 include Chronic Mountain Sickness. Among its related pathways are Central carbon metabolism in cancer and B Cell Receptor Signaling Pathway (sino). Gene Ontology (GO) annotations related to this gene include protein kinase activity and pyruvate dehydrogenase (acetyl-transferring) kinase activity. An important paralog of this gene is PDK2.
Related Pathway/CSCs feature
 SOX9-PDK1 axis is essential for glioma stem cell self-renewal and temozolomide resistance.
Oncotarget.2017 Nov 30;9(1):192-204.. [ 29416606 ]