Detail for HMGA2


Full Name

High mobility group protein A2

Gene Name

GC06P041845

NCBI ID

Related Disease

  • Gastric cancer [ref.1]

Therapy Method

  • [ref.]

Function

HMGA2 (High Mobility Group AT-Hook 2) is a Protein Coding gene. Diseases associated with HMGA2 include Salivary Gland Adenoma, Pleomorphic and Silver-Russell Syndrome. Among its related pathways are MicroRNAs in cancer and DNA Damage/Telomere Stress Induced Senescence. Gene Ontology (GO) annotations related to this gene include enzyme binding and transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding.

Related Pathway/CSCs feature

Reference

  • [1] HMGA2 regulates epithelial-mesenchymal transition and the acquisition of tumor stem cell properties through TWIST1 in gastric cancer.
    Oncol Rep.2017 Jan;37(1):185-192.. [ 27878307 ]

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