Detail for miR‑196a‑5p


Full Name

MicroRNA-196a-5p

Gene Name

NCBI ID

Related Disease

  • Gastric cancer [ref.1]

Therapy Method

  • [ref.]

Function

HMGA2 (High Mobility Group AT-Hook 2) is a Protein Coding gene. Diseases associated with HMGA2 include Salivary Gland Adenoma, Pleomorphic and Silver-Russell Syndrome. Among its related pathways are MicroRNAs in cancer and DNA Damage/Telomere Stress Induced Senescence. Gene Ontology (GO) annotations related to this gene include enzyme binding and transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding.

Related Pathway/CSCs feature

Reference

  • [1] miR‑196a‑5p modulates gastric cancer stem cell characteristics by targeting Smad4.
    Int J Oncol.2017 Jun;50(6):1965-1976.. [ 28440445 ]

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