Detail for miR-520b


Full Name

MicroRNA-520b

Gene Name

NCBI ID

Related Disease

  • Head-neck cancer [ref.1]

Therapy Method

  • [ref.]

Function

HMGA2 (High Mobility Group AT-Hook 2) is a Protein Coding gene. Diseases associated with HMGA2 include Salivary Gland Adenoma, Pleomorphic and Silver-Russell Syndrome. Among its related pathways are MicroRNAs in cancer and DNA Damage/Telomere Stress Induced Senescence. Gene Ontology (GO) annotations related to this gene include enzyme binding and transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding.

Related Pathway/CSCs feature

Reference

  • [1] MiR-520b as a novel molecular target for suppressing stemness phenotype of head-neck cancer by inhibiting CD44.
    Sci Rep.2017 May 17;7(1):2042.. [ 28515423 ]

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