Detail for miR‑181b‑5p


Full Name

MicroRNA-181b-5p

Gene Name

Related Disease

  • Non-small cell lung cancer [ref.]

Therapy Method

  • [ref.]

Function

HMGA2 (High Mobility Group AT-Hook 2) is a Protein Coding gene. Diseases associated with HMGA2 include Salivary Gland Adenoma, Pleomorphic and Silver-Russell Syndrome. Among its related pathways are MicroRNAs in cancer and DNA Damage/Telomere Stress Induced Senescence. Gene Ontology (GO) annotations related to this gene include enzyme binding and transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding.

Related Pathway/CSCs feature

Reference

  • [1] miR‑181b‑5p mediates TGF‑β1-induced epithelial-to-mesenchymal transition in non-small cell lung cancer stem-like cells derived from lung adenocarcinoma A549 cells.
    Int J Oncol.2017 Jul;51(1):158-168.. [ 28534939 ]

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