Detail for miR-217


Full Name

MicroRNA-127

Gene Name

GC02M055982

NCBI ID

Related Disease

  • Hepatocellular carcinoma [ref.1]

Therapy Method

  • [ref.]

Function

HMGA2 (High Mobility Group AT-Hook 2) is a Protein Coding gene. Diseases associated with HMGA2 include Salivary Gland Adenoma, Pleomorphic and Silver-Russell Syndrome. Among its related pathways are MicroRNAs in cancer and DNA Damage/Telomere Stress Induced Senescence. Gene Ontology (GO) annotations related to this gene include enzyme binding and transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding.

Related Pathway/CSCs feature

Reference

  • [1] miR-217 targeting DKK1 promotes cancer stem cell properties via activation of the Wnt signaling pathway in hepatocellular carcinoma.
    Oncol Rep.2017 Oct;38(4):2351-2359.. [ 28849121 ]

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