Detail for CD24+/CD44+ Melanoma cells


Full Name

CD24+/CD44+ melanoma tumor cells

Gene Name

Related Disease

  • Melanoma tumor [ref.1]

Therapy Method

Function

The melanoma tumor cell subpopulations were analyzed and sorted according to the expression of CD24 and CD44 markers. They were classified into four groups, including CD44+/CD24+, CD44+/CD24, CD44/CD24+ and CD44/CD24. Regarding the higher tumorigenic and spheroid formation abilities of CD24+/CD44+ double-positive cells, they were considered as melanoma stem cells and used for immunotherapy.

Related Pathway/CSCs feature

  • Not Detected

Reference

  • [1] Dendritic cell based immunotherapy using tumor stem cells mediates potent antitumor immune responses.
    Dashti, A., et al. (2016). Cancer Lett 374(1): 175-185. [ 26803056 ]

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