Detail for c-Myb


Full Name

Transcriptional activator Myb

Uniprot ID

Gene Name

MYB

NCBI ID

Related Disease

  • Liver Cancer [ref.1]

Therapy Method

Function

Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Reference

  • [1] microRNA-150 inhibits human CD133-positive liver cancer stem cells through negative regulation of the transcription factor c-Myb.
    Zhang, J., et al. (2012). Int J Oncol 40(3): 747-756. [ 22025269 ]

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