Detail for microRNA 101


Full Name

microRNA 101

Gene Name

MIR101

NCBI ID

Related Disease

  • Pancreatic Cancer [ref.1]

Therapy Method

Function

miR-101 microRNA precursor is a small non-coding RNA that regulates gene expression. Expression of miR-101 has been validated in both human (MI0000103, MI0000739) and mouse (MI0000148). This microRNA appears to be specific to the vertebrates and has now been predicted or confirmed in a wide range of vertebrate species (MIPF0000046). The precursor microRNA is a stem-loop structure of about 70 nucleotides in length that is processed by the Dicer enzyme to form the 21-24 nucleotide mature microRNA. In this case the mature sequence is excised from the 3' arm of the hairpin. 

Related Pathway/CSCs feature

Reference

  • [1] Curcumin analogue CDF inhibits pancreatic tumor growth by switching on suppressor microRNAs and attenuating EZH2 expression.
    Bao, B., et al. (2012). Cancer Res 72(1): 335-345.. [ 22108826 ]

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