Drug name: Hexaminolevulinate + PDT


Related CSCTT Targets

CD45 [ref.1]P08575

Hexaminolevulinate, 5-aminolevulinic acid hexyl ester

Cas.no PubChem ID
140898-97-1 6433083
Known Target
Structure
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Introduction
Hexaminolevulinate is an imaging agent that is used in a procedure for the bladder called cystoscopy. Imaging agents help create an image or picture of body parts, such as the bladder. Hexaminolevulinate is used to check for cancer cells in the bladder.

PDT, Photodynamic therapy

Cas.no PubChem ID
Known Target
Structure
...
Introduction
Photodynamic therapy (PDT) is a form of phototherapy using nontoxic light-sensitive compounds that are exposed selectively to light, whereupon they become toxic to targeted malignant and other diseased cells. PDT has proven ability to kill microbial cells, including bacteria, fungi and viruses. PDT is popularly used in treating acne. It is used clinically to treat a wide range of medical conditions, including wet age-related macular degeneration and malignant cancers, and is recognised as a treatment strategy which is both minimally invasive and minimally toxic.

Reference

  • [1] Tissue responses to hexyl 5-aminolevulinate-induced photodynamic treatment in syngeneic orthotopic rat bladder cancer model: possible pathways of action. Arum, C. J., et al. (2011).J Biomed Opt. 16(2):028001.
    21361708. [ 21361708 ]

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