Drug name: p19ARF

Related CSCTT Targets

FOXM1 [ref.1]Q08050

FOXM1 selective alternate reading frame peptide inhibitor

Cas.no PubChem ID
Known Target
Forkhead box protein M1Q08050
Sequence: HIPRLTGEWAAPGAPAAVA. p19ARF is a selective FOXM1 peptide inhibitor, highly effective in restoring endocrine sensitivity and suppressing breast cancer aggressiveness. This ARF inhibitor has already been shown to be effective in suppressing the development of hepatocellular carcinoma in a pre-clinical model.


  • [1] The forkhead transcription factor FOXM1 promotes endocrine resistance and invasiveness in estrogen receptor-positive breast cancer by expansion of stem-like cancer cells. Bergamaschi, A., et al. (2014).Breast Cancer Res.16(5):436.
    25213081. [ 25213081 ]

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