Drug name: Chloramphenicol


Related CSCTT Targets

ALDH1 [ref.1]P00352

Chloramphenicol

Cas.no PubChem ID
56-75-7 298
Known Target
Complement decay-accelerating factorP08174
50S ribosomal protein L16P0ADY7
Dr hemagglutinin structural subunitP24093
Introduction
Chloramphenicol is a broad-spectrum antibiotic that was derived from the bacterium Streptomyces venezuelae and is now produced synthetically. It is effective against a wide variety of microorganisms, but due to serious side-effects (e.g., damage to the bone marrow, including aplastic anemia) in humans, it is usually reserved for the treatment of serious and life-threatening infections (e.g., typhoid fever).

Chloramphenicol-Structure

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Reference

  • [1] Suppressing glioblastoma stem cell function by aldehyde dehydrogenase inhibition with chloramphenicol or disulfiram as a new treatment adjunct: an hypothesis. Kast, R. E., et al. (2009).Curr Stem Cell Res Ther.4(4):314-7.
    19500061. [ 19500061 ]

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