Drug name: DEAB


Related CSCTT Targets

ALDH1 [ref.1, 2]P00352

DEAB, 4-(diethylamino)benzaldehyde

Cas.no PubChem ID
120-21-8 67114
Known Target
Retinal dehydrogenase 1P00352
Introduction
A specific ALDH inhibitor.

DEAB, 4-(diethylamino)benzaldehyde-Structure

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Reference

  • [1] High aldehyde dehydrogenase activity enhances stem cell features in breast cancer cells by activating hypoxia-inducible factor-2α. Kim, R. J., et al. (2013).Cancer Lett.333(1):18-31.
    23174107. [ 23174107 ]
  • [2] Cisplatin-resistant cells in malignant pleural mesothelioma cell lines show ALDH(high)CD44(+) phenotype and sphere-forming capacity. Cortes-Dericks, L., et al. (2014).BMC Cancer.14:304.
    24884875. [ 24884875 ]

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