|DNA topoisomerase 2-alpha||P11388|
|Protein-tyrosine kinase 2-beta||Q14289|
|Nuclear receptor coactivator 1||Q15788|
|Nuclear receptor coactivator 2||Q15596|
|An isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA topoisomerases, type II) activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 phase arrest in human and murine cell lines. Additionally, genistein has antihelmintic activity. It has been determined to be the active ingredient in Felmingia vestita, which is a plant traditionally used against worms. It has also been demonstrated to be effective against intestinal parasites such as the common liver fluke, pork trematode and poultry cestode.