Drug name: Thioridazine


Related CSCTT Targets

Dopamine receptor D5 [ref.1]P21918

Thioridazine

Cas.no PubChem ID
50-52-2 5452
Known Target
50S ribosomal protein L24eP14116
D(1A) dopamine receptorP21728
Alpha-1A adrenergic receptorP35348
Alpha-1B adrenergic receptorP35368
5-hydroxytryptamine receptor 2AP28223
Potassium voltage-gated channel subfamily H member 2Q12809
Introduction
A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine.

Thioridazine-Structure

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Reference

  • [1] Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells. Sachlos, E., et al. (2012).Cell. 149(6):1284-97.
    22632761. [ 22632761 ]

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