Detail for SOX2

Full Name

SRY-Box 2

Gene Name



Related Disease

  • breast cancer [ref.1]

Therapy Method

  • [ref.]


SOX2 (SRY-Box 2) is a Protein Coding gene. Diseases associated with SOX2 include Microphthalmia, Syndromic 3 and Tracheoesophageal Fistula. Among its related pathways are Transcriptional Regulatory Network in Embryonic Stem Cell and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and protein heterodimerization activity. An important paralog of this gene is SOX3.

Related Pathway/CSCs feature


  • [1] SOX2 Is a Marker for Stem-like Tumor Cells in Bladder Cancer.
    Stem Cell Reports.2017 Aug 8;9(2):429-437. [ 28793245 ]

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