Detail for Cisplatin-resistant cervical cancer cells


Full Name

Cisplatin-resistant cervical cancer cells

Gene Name

Related Disease

  • Cervical Cancer [ref.1]

Therapy Method

Function

Although cisplatin is the most effective agent for metastatic cervical cancer, prolonged treatment induces multiple mechanisms of tumor resistance and is associated with significant toxicity. Therefore, the development of new cisplatin formulations to overcome both resistance and toxicity remains a high priority and is crucial for a better treatment and a more prolonged survival.

Related Pathway/CSCs feature

  • Not Detected

Reference

  • [1] Preclinical evaluation of a new liposomal formulation of cisplatin, lipoplatin, to treat cisplatin-resistant cervical cancer.
    Casagrande, N., et al. (2013). Gynecol Oncol 131(3): 744-752.. [ 24029417 ]
  • [2] Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is involved in cervical cancer stemness and can be a target of immunotherapy.
    Asano, T., et al. (2016). Oncotarget 7(10): 11223-11237. [ 26849232 ]

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