Detail for CK2


Full Name

Casein kinase II

Gene Name

CSNK2A1, CSNK2A2, CSNK2B

Related Disease

  • Glioblastoma [ref.1]

Therapy Method

Function

Protein kinase CK2 is a ubiquitously expressed serine/threonine kinase composed of two catalytic subunits (α) and/or (α′) and two regulatory (β) subunits. The expression and kinase activity of CK2 is elevated in many different cancers, including glioblastoma (GBM). 

Reference

  • [1] Protein kinase CK2 is important for the function of glioblastoma brain tumor initiating cells.
    J Neurooncol.2017 Apr;132(2):219-229. [ 28181105 ]

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