Detail for WNT5A


Full Name

Wnt Family Member 5A

Gene Name

GC03M055474

NCBI ID

Related Disease

  • PAN [ref.1]
  • human gastric carcinoma [ref.2]

Therapy Method

  • [ref.]

Function

WNT5A (Wnt Family Member 5A) is a Protein Coding gene. Diseases associated with WNT5A include Robinow Syndrome, Autosomal Dominant 1 and Robinow Syndrome. Among its related pathways are Presynaptic function of Kainate receptors and HTLV-I infection. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and protein domain specific binding. An important paralog of this gene is WNT5B.

Related Pathway/CSCs feature

Reference

  • [1] Niche WNT5A regulates the actin cytoskeleton during regeneration of hematopoietic stem cells.
    J Exp Med.2017 Jan;214(1):165-181. [ 27998927 ]
  • [2] WNT5A is a key regulator of the epithelial-mesenchymal transition and cancer stem cell properties in human gastric carcinoma cells.
    Pathobiology.2013;80(5):235-44. [ 23615002 ]

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