SETD2 (SET Domain Containing 2) is a Protein Coding gene. Diseases associated with SETD2 include Luscan-Lumish Syndrome and Sotos Syndrome 1. Among its related pathways are Chromatin organization and PKMTs methylate histone lysines. Gene Ontology (GO) annotations related to this gene include histone-lysine N-methyltransferase activity. An important paralog of this gene is ASH1L.
Related Pathway/CSCs feature
 ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models.
Mol Cancer.2016 Mar 22;15:26. [ 27001172 ]
 HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progression.
Carcinogenesis.2013 Aug;34(8):1699-707. [ 23740838 ]