Detail for CD44


Full Name

CD44 Molecule (Indian Blood Group)

Gene Name

GC11P035168

NCBI ID

Related Disease

  • PAN [ref.1,2]

Therapy Method

  • [ref.]

Function

CD44 (CD44 Molecule (Indian Blood Group)) is a Protein Coding gene. Diseases associated with CD44 include Superficial Keratitis and Lichen Sclerosus. Among its related pathways are Cell adhesion_ECM remodeling and G-protein signaling G-Protein alpha-i signaling cascades. Gene Ontology (GO) annotations related to this gene include transmembrane signaling receptor activity and cytokine receptor activity. An important paralog of this gene is LYVE1.

Related Pathway/CSCs feature

Reference

  • [1] CD44: More than a mere stem cell marker.
    Int J Biochem Cell Biol.2016 Dec;81(Pt A):166-173. [ 27640754 ]
  • [2] CD44 integrates signaling in normal stem cell, cancer stem cell and (pre)metastatic niches.
    Exp Biol Med (Maywood).2013 Mar;238(3):324-38. [ 23598979 ]

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