Detail for BMP9


Full Name

Human bone morphogenetic protein 9/Growth Differentiation Factor 2

Gene Name

GC10P047322

NCBI ID

Related Disease

  • human breast cancer [ref.1]
  • breast cancer [ref.2]

Therapy Method

  • [ref.]

Function

GDF2 (Growth Differentiation Factor 2) is a Protein Coding gene. Diseases associated with GDF2 include Telangiectasia, Hereditary Hemorrhagic, Type 5 and Hereditary Hemorrhagic Telangiectasia. Among its related pathways are ERK Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include cytokine activity and transforming growth factor beta receptor binding. An important paralog of this gene is BMP10.

Related Pathway/CSCs feature

Reference

  • [1] Biological roles of human bone morphogenetic protein 9 in the bone microenvironment of human breast cancer MDA-MB-231 cells.
    Am J Transl Res.2015 Sep 15;7(9):1660-74. [ 26550465 ]
  • [2] BMP9 regulates cross-talk between breast cancer cells and bone marrow-derived mesenchymal stem cells.
    Cell Oncol (Dordr).2014 Oct;37(5):363-75. [ 25209393 ]

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