Detail for uPAR


Full Name

Urokinase receptor

Gene Name

GC19M043646

NCBI ID

Related Disease

  • oral cancer [ref.1]

Therapy Method

  • [ref.]

Function

PLAUR (Plasminogen Activator, Urokinase Receptor) is a Protein Coding gene. Diseases associated with PLAUR include Ureter, Cancer Of and Perforated Corneal Ulcer. Among its related pathways are Cell adhesion_ECM remodeling and Apoptotic Pathways in Synovial Fibroblasts. Gene Ontology (GO) annotations related to this gene include signaling receptor binding.

Related Pathway/CSCs feature

Reference

  • [1] Cleavage of the urokinase receptor (uPAR) on oral cancer cells: regulation by transforming growth factor - β1 (TGF-β1) and potential effects on migration and invasion.
    BMC Cancer.2017 May 19;17(1):350. [ 28526008 ]

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