Detail for TGF-β


Full Name

Transforming growth factor-β

Gene Name

GC19M041301

NCBI ID

Related Disease

  • breast cancer [ref.1]

Therapy Method

  • [ref.]

Function

TGFB1 (Transforming Growth Factor Beta 1) is a Protein Coding gene. Diseases associated with TGFB1 include Camurati-Engelmann Disease and Cystic Fibrosis. Among its related pathways are ERK Signaling and Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and enzyme binding. An important paralog of this gene is TGFB3.

Related Pathway/CSCs feature

Reference

  • [1] Crosstalk between TGF-β signaling and miRNAs in breast cancer metastasis.
    Tumour Biol.2016 Aug;37(8):10011-9. [ 27153853 ]

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