Detail for REST

Full Name

The repressor element (RE)-1 silencing transcription factor

Gene Name



Related Disease

  • PAN [ref.1]

Therapy Method

  • [ref.]


REST (RE1 Silencing Transcription Factor) is a Protein Coding gene. Diseases associated with REST include Wilms Tumor 6 and Fibromatosis, Gingival, 5. Among its related pathways are Transcriptional Regulatory Network in Embryonic Stem Cell and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and transcription factor binding. An important paralog of this gene is ZNF407.

Related Pathway/CSCs feature


  • [1] REST and the RESTless: in stem cells and beyond.
    Future Neurol.2009;4(3):317-329. [ 19885378 ]

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