Detail for PYK2


Full Name

Proline-rich tyrosine kinase 2

Gene Name

GC08P027311

NCBI ID

Related Disease

  • multiple myeloma [ref.1]

Therapy Method

  • [ref.]

Function

PTK2B (Protein Tyrosine Kinase 2 Beta) is a Protein Coding gene. Diseases associated with PTK2B include Transient Cerebral Ischemia and Osteoporosis. Among its related pathways are ERK Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is PTK2.

Related Pathway/CSCs feature

Reference

  • [1] Targeting PYK2 mediates microenvironment-specific cell death in multiple myeloma.
    Oncogene.2016 May;35(21):2723-34. [ 26387544 ]

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