Detail for MLL1


Full Name

Mixed-lineage leukemia 1

Gene Name

GC11P118436

NCBI ID

Related Disease

  • glioma [ref.1]

Therapy Method

  • [ref.]

Function

KMT2A (Lysine Methyltransferase 2A) is a Protein Coding gene. Diseases associated with KMT2A include Wiedemann-Steiner Syndrome and Cornelia De Lange Syndrome 1. Among its related pathways are Circadian rythm related genes and Chromatin organization. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and identical protein binding. An important paralog of this gene is KMT2B.

Related Pathway/CSCs feature

Reference

  • [1] Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential.
    Cell Death Differ.2012 Mar;19(3):428-39. [ 21836617 ]

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