Detail for LSD1


Full Name

Lysine-specific demethylase 1

Gene Name

GC01P023019

NCBI ID

Related Disease

  • breast cancer [ref.1]

Therapy Method

  • [ref.]

Function

KDM1A (Lysine Demethylase 1A) is a Protein Coding gene. Diseases associated with KDM1A include Cleft Palate, Psychomotor Retardation, And Distinctive Facial Features and Kbg Syndrome. Among its related pathways are Signaling by Rho GTPases and Coregulation of Androgen receptor activity. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and enzyme binding. An important paralog of this gene is KDM1B.

Related Pathway/CSCs feature

Reference

  • [1] LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer.
    Sci Rep.2018 Jan 8;8(1):73. [ 29311580 ]

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