Detail for ITGB5


Full Name

Integrin β5

Gene Name

GC03M124761

NCBI ID

Related Disease

  • breast cancer [ref.1]

Therapy Method

  • [ref.]

Function

ITGB5 (Integrin Subunit Beta 5) is a Protein Coding gene. Diseases associated with ITGB5 include Villous Adenocarcinoma and Arrhythmogenic Right Ventricular Cardiomyopathy. Among its related pathways are ERK Signaling and Focal Adhesion. Gene Ontology (GO) annotations related to this gene include integrin binding. An important paralog of this gene is ITGB3.

Related Pathway/CSCs feature

Reference

  • [1] Integrin β5 contributes to the tumorigenic potential of breast cancer cells through the Src-FAK and MEK-ERK signaling pathways.
    Oncogene.2013 Jun 20;32(25):3049-58. [ 22824793 ]

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