Detail for ISG15


Full Name

ISG15 Ubiquitin-Like Modifier

Gene Name

GC01P001001

NCBI ID

Related Disease

  • pancreatic cancer [ref.1]

Therapy Method

  • [ref.]

Function

ISG15 (ISG15 Ubiquitin-Like Modifier) is a Protein Coding gene. Diseases associated with ISG15 include Immunodeficiency 38 With Basal Ganglia Calcification and Influenza. Among its related pathways are RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways and Transport of the SLBP independent Mature mRNA. Gene Ontology (GO) annotations related to this gene include protein tag. An important paralog of this gene is UBC.

Related Pathway/CSCs feature

Reference

  • [1] ISG15 is a critical microenvironmental factor for pancreatic cancer stem cells.
    Cancer Res.2014 Dec 15;74(24):7309-20. [ 25368022 ]

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