FGF2 (Fibroblast Growth Factor 2) is a Protein Coding gene. Diseases associated with FGF2 include Kaposi Sarcoma and Corneal Neovascularization. Among its related pathways are ERK Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include cytokine activity and heparin binding. An important paralog of this gene is FGF1.
bFGF, which belongs to the heparin binding growth factor family, mediates various cellular events, including proliferation, motility, and differentiation. bFGF increases embryonic myogenic cell migration in a dose-dependent manner. bFGF also plays an important role in the proliferation and stem cell plasticity of adipose-derived stem cells. Furthermore, bFGF can activate normal fibroblasts and give them properties that are analogous to those of CAFs