Detail for HGF


Full Name

Hepatocyte growth factor

Uniprot ID

Gene Name

HGF

NCBI ID

Related Disease

  • Colon Cancer [ref.1]

Therapy Method

Function

Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

Reference

  • [1] Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.
    Vermeulen, L., et al. (2010). Nat Cell Biol 12(5): 468-476.. [ 20418870 ]

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