Detail for c-Myc


Full Name

Myc proto-oncogene protein

Uniprot ID

Gene Name

MYC

NCBI ID

Related Disease

  • Glioblastoma [ref.1]

Therapy Method

Function

Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

Reference

  • [1] c-Myc is required for maintenance of glioma cancer stem cells.
    Wang, J., et al. (2008). PLoS One 3(11): e3769.. [ 19020659 ]

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