Detail for IL-4


Full Name

Interleukin-4

Uniprot ID

Gene Name

IL4

NCBI ID

Related Disease

  • Colon Cancer [ref.1]

Therapy Method

Function

Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.

Reference

  • [1] .Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4.
    Todaro, M., et al. (2007). Cell Stem Cell 1(4): 389-402.. [ 18371377 ]

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