Detail for FLI1


Full Name

Friend leukemia integration 1 transcription factor

Uniprot ID

Gene Name

FLI1

NCBI ID

Related Disease

  • Ewing’s Sarcoma [ref.1]

Therapy Method

Function

Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.

Reference

  • [1] High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition.
    Awad, O., et al. (2010). PLoS One 5(11): e13943.. [ 21085683 ]

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